Discussion about this post

User's avatar
John Lawrence Aspden's avatar

I'm most interested to see what happens next. Your graph looks like exponential decay to a set point just below where you are now. I'd be actively surprised if your second go causes another big drop, so if it does, call me on it and remind me that I've made a confident false prediction; and so must be wrong about something important (probably the whole lipostat idea).

This 'food anhedonia' that you describe sounds awfully like what I get if I overeat, or what I'm currently getting trying ex150ish+fruit. You're just not interested in eating at all.

I think that's 'lipostat realises you're carrying too much fat, and so stops motivating you to eat (at least as long as you're not short of protein or micronutrients, in which case you get very specific cravings).

My guess for what's going on is that dropping the sauce has reduced your protein intake, and that that's important for some reason. But it might be the vinegar, acetic acid bypasses beta-oxidation and glycolysis and gets fed straight into the Krebs Cycle, and that might be important too. Did you get similar results trying either separately, I can't remember?

You're probably sailing awfully close to protein deficiency now. If you get cheeseburger cravings, have a cheeseburger as soon as possible!

Expand full comment
Lucas's avatar

Interesting, thanks for sharing!

>If tomato sauce at lunch makes whipped cream at dinner more palatable, that’s some quantum entanglement stuff if I’ve ever seen it.

Weirdly for me when I eat lean protein (chicken breast, protein powder, etc) I feel some kind of urge to eat in waves all day. I have no idea what are the "timings" on the different "feedback loops", but I think it's possible to trigger hyperphagia from one meal to another.

Expand full comment
31 more comments...

No posts